Guadalupe Comillo, known to her friends as Lupe, is an activist from Los Angeles, California.
In 2007, Guadalupe is birdwatching at Icicle Creek Lodge. However, when Nancy discovers a torn magazine cover in the ransacked ice fishing lodge with the phone number for Run and Grow Free on it, she gets Guadalupe to confess that she is a member of that organization, which is dedicated to preserving wild animals, and she is at the lodge in order to make sure the white wolf in the area isn't hurt. She ransacked the ice fishing lodge and also made sure that Ollie's rifle would miss the wolf.
When Ollie finds out about his rifle, he makes Guadalupe leave the lodge, at which point she leaves her phone number for Nancy.